Buy O-PCE Pellets 10mg Online | High-Purity Arylcyclohexylamine Research Chemical
Introduction to Buy O-PCE Pellets 10mg
Buy O-PCE Pellets 10mg (2-Oxo-PCE / Eticyclidone), designated in pharmacological literature as a novel synthetic arylcyclohexylamine, is a highly potent research chemical and a critical reference standard in neuropharmacological and forensic research. Structurally, it is the 2-oxo analog of PCE (Eticyclidine) and belongs to the same chemical class as ketamine, MXE (Methoxetamine), and DCK (Deschloroketamine).
In neuropharmacological research, the addition of the 2-oxo (ketone) group to the cyclohexane ring is a critical structural modification that fundamentally alters the molecule’s pharmacokinetic profile, generally reducing pure receptor affinity while significantly extending metabolic stability and duration of action. O-PCE functions as a potent non-competitive NMDA receptor antagonist, binding to the PCP site within the NMDA receptor complex and blocking glutamate-gated ion channels. Because arylcyclohexylamines are potent CNS depressants active in the low milligram range, handling bulk powder poses severe risks of accidental exposure and dosing errors. To solve this critical safety and accuracy challenge, we supply O-PCE in precision-dosed 10mg pressed pellets. This format guarantees absolute dosing consistency, eliminates the hazards associated with loose powders, and provides a highly convenient metric for streamlined volumetric preparation (e.g., dissolving one 10mg pellet in 10mL of solvent yields an exact 1mg/mL standard). Note: This product is strictly intended for in-vitro research and analytical purposes only.
Key Features and Benefits – Buy O-PCE Pellets 10mg
- Absolute Dosing Precision: Each pellet contains exactly 10mg of O-PCE HCl, eliminating the life-threatening risk of micro-weighing errors inherent with active bulk powders and ensuring absolute consistency across your research assays.
- Streamlined Volumetric Preparation: The 10mg metric provides a highly convenient, standardized reference mass for easy mathematical dilution (e.g., yielding exactly 1mg/mL in 10mL, or 0.1mg/mL in 100mL) without the fractional calculations required by random bulk powder masses.
- Enhanced Laboratory Safety: The pressed pellet format drastically reduces the risk of accidental aerial dispersion or transdermal absorption, which is a severe hazard with loose, potent dissociative powders.
- 2-Oxo SAR Mapping: O-PCE provides researchers with a vital tool to study the structural-activity relationships (SAR) of 2-oxo substituted arylcyclohexylamines, mapping how the ketone group alters NMDA receptor affinity and metabolic clearance compared to its non-oxo parent (PCE).
- Enhanced Compound Stability: Arylcyclohexylamines are sensitive to light, moisture, and oxygen. The pressed pellet matrix physically shields the active molecule from ambient elements, drastically extending the chemical’s viable shelf life.
Product Specifications
- Chemical Name: 1-(1-Phenylcyclohexyl)ethan-1-amine hydrochloride (2-Oxo-PCE HCl)
- Common Designation: O-PCE / 2-Oxo-PCE / Eticyclidone
- CAS Number: 14030-29-6 (Freebase)
- Class: Arylcyclohexylamine / NMDA Antagonist / Research Chemical
- Dosage per Unit: 10 mg (Precisely measured and pressed)
- Format: Pressed pellets in tamper-evident, light-resistant packaging
- Purity: ≥ 98% (Verified by Independent Third-Party Testing)
- Appearance: White to off-white pressed solid pellets (shape/color varies by batch)
- Storage Requirements: Store in a cool, dry, dark environment (ideally -20°C for long-term archival). Keep in original packaging to protect from light and humidity.
- Solubility: Freely soluble in water and aqueous buffers once extracted from the pellet matrix.
Applications and Usage
O-PCE 10mg Pellets are exclusively designated for in-vitro (outside a living organism) research and analytical applications. Common laboratory applications include:
- Volumetric Standard Preparation: Utilizing the exact 10mg metric to create large-volume, precisely concentrated stock solutions for high-throughput screening and sub-micromolar assay preparation.
- NMDA Receptor Binding Assays: Investigating the compound’s affinity and efficacy as a non-competitive antagonist at the PCP binding site on the NMDA receptor using isolated neuronal membrane preparations.
- Structural-Activity Relationship (SAR) Mapping: Contrasting the pharmacokinetic properties and receptor conformational changes induced by 2-oxo substitution (O-PCE) versus non-oxo substitution (PCE) and methoxy substitution (MXE) to map the steric limits of the receptor binding pocket.
- Metabolic Pathway Studies: Analyzing the hepatic breakdown and enzymatic hydroxylation of 2-oxo arylcyclohexylamines using hepatocyte cultures and liver microsomes, comparing its stability to ketamine and DCK.
- Forensic and Analytical Calibration: Utilizing the precisely dosed 10mg pellet as a known quantitative standard for LC/MS and GC/MS spectroscopy to validate analytical instruments and detect O-PCE and its unique biomarkers in biological matrices.
Disclaimer: This product is not for human or veterinary consumption. It must only be handled in controlled laboratory environments by qualified professionals.
Purity and Testing
We guarantee a purity level of ≥ 98% for the O-PCE utilized in our pellets. Because dosing at the 10mg level requires absolute manufacturing precision, every production batch undergoes rigorous, independent third-party testing to verify chemical identity, absolute purity, dosage accuracy, and blend uniformity (ensuring every individual pellet contains exactly 10mg of active ingredient). We also perform exhaustive screening to ensure the absolute absence of dangerous substituted arylcyclohexylamine contaminants (such as MXE, Ketamine, or 2-Fluorodeschloroketamine). Certificates of Analysis (CoA) and Safety Data Sheets (SDS) are provided upon request.
Safety and Handling
WARNING: O-PCE IS A HIGHLY POTENT NMDA ANTAGONIST AND CENTRAL NERVOUS SYSTEM DEPRESSANT. EXTREME CAUTION IS REQUIRED.
- Personal Protective Equipment (PPE): Must wear nitrile gloves, chemical-resistant safety goggles, and a P100 particulate respirator when handling the pellets or extracting the compound.
- Extraction Safety: When crushing or dissolving the 10mg pellet to extract the dose for assays, do so within a certified chemical fume hood using appropriate non-sparking tools.
- Accidental Exposure: If skin contact occurs, wash thoroughly with soap and water immediately. Seek medical attention if physiological effects occur. Note: Standard opioid antagonists (e.g., Naloxone) are generally ineffective against dissociative overdose; benzodiazepines are typically required for severe adverse events.
- Secure Storage: Keep pellets locked away in a secure, access-controlled laboratory cabinet, out of reach of unauthorized personnel.
Global Shipping and Discreet Delivery
- Global Reach: We ship O-PCE Pellets internationally, complying with all hazardous materials shipping regulations.
- Discreet Packaging: Orders are dispatched in unmarked, tamper-evident packaging. The uniform shape of supplement bottles makes them exceptionally easy to ship discreetly without attracting unwanted attention.
- Rapid Processing: Orders are processed and shipped within 24 hours of cleared payment with full end-to-end tracking.
- Damage Prevention: Pellet containers are cushioned within rigid outer boxes to prevent crushing during international transit.
Why Choose Us To Buy O-PCE Pellets 10mg?
- Innovative Delivery Formats: We are pioneers in providing high-potency research chemicals in precision-dosed, laboratory-friendly formats that prioritize safety and volumetric accuracy over dangerous bulk powders.
- Uncompromising Quality: We verify every batch in-house and via third-party labs—including exhaustive contaminant screening and blend uniformity testing—before it reaches you.
- Total Transparency: Full analytical data provided—no fillers, no impurities, just verified 10mg reference units.
- Secure Transactions: We utilize SSL encryption and accept secure, discreet payment methods, including major cryptocurrencies (Bitcoin, Monero, Ethereum) and secure bank transfers.
Legal and Safety Compliance
O-PCE 10mg Pellets are sold strictly as research chemicals and are not approved by the FDA, EMA, or any equivalent regulatory body for human or veterinary use.
It is the sole responsibility of the purchaser to ensure that the acquisition, possession, and use of O-PCE comply with all local, state, national, and international laws. Warning: O-PCE is a potent central nervous system depressant and NMDA antagonist. Ingestion can cause severe, life-threatening psychological and physiological effects, including profound dissociation, respiratory depression, and severe psychological distress. It may fall under federal analogue acts or specific NPS legislation in various jurisdictions. We do not ship to regions where this compound is explicitly prohibited. By purchasing from us, you affirm that you are a qualified researcher or institutional buyer over the age of 18, and you assume all legal liability for the product upon delivery.
Frequently Asked Questions (FAQ)
Q1: What is O-PCE?
A: O-PCE (2-Oxo-PCE / Eticyclidone) is a novel synthetic arylcyclohexylamine. It is the 2-oxo analog of PCE (Eticyclidine). It acts primarily as a potent non-competitive NMDA receptor antagonist (dissociative), blocking the glutamate-gated ion channels in vitro.
Q2: Why choose 10mg pellets over bulk O-PCE powder?
A: The 10mg pressed pellet guarantees an exact, pre-measured reference mass, removing the risk of micro-weighing errors associated with potent bulk powders. The specific 10mg metric is highly optimized for streamlined volumetric dilution—dissolving one pellet in 10mL of solvent instantly creates an exact 1mg/mL solution, eliminating complex fractional math and saving significant laboratory preparation time.
Q3: What makes O-PCE different from PCE or Ketamine?
A: While all three are NMDA antagonists, the structural modifications dictate their pharmacokinetics. PCE lacks the 2-oxo group, making it faster-acting but shorter-lived. Ketamine features a 2-chloro group on the phenyl ring, while O-PCE retains the unsubstituted phenyl ring but adds the 2-oxo group. The 2-oxo group (shared with Ketamine and MXE) alters metabolic stability and receptor binding kinetics, making it essential for comparative SAR research.
Q4: Can the contents of the pellet be consumed?
A: Absolutely NOT. O-PCE is a potent NMDA antagonist and CNS depressant. It is sold strictly for in-vitro laboratory and analytical research. Ingestion can cause unpredictable, severe psychological and cardiovascular effects and is strictly prohibited.
Q5: Do you provide a Certificate of Analysis (CoA)?
A: Yes. We provide a comprehensive CoA—including HPLC, GC/MS, and dosage verification data—for every pellet batch we sell. This guarantees the identity, purity, and exact 10mg mass of the compound.
Q6: Is it legal to buy O-PCE in my country?
A: Legality varies drastically by country and is subject to change. Because it is structurally related to controlled dissociatives like PCE and ketamine, it is often controlled under analogue acts or specific NPS bans. We cannot provide legal advice. It is your responsibility to research your local laws regarding this compound before placing an order.
Q7: How should I store O-PCE Pellets for long-term research?
A: Store the pellets in their original, tightly sealed container in a cool, dry, dark place (room temperature is typically sufficient, or 4°C for long-term storage). Keep away from direct sunlight, heat, and moisture to prevent degradation of the active ingredient.




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