Buy 5BR-ADB-INACA Powder Online | High-Purity Brominated Indazoleacetamide Research Chemical

Introduction to Buy 5BR-ADB-INACA Powder

Buy 5BR-ADB-INACA Powder (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5-bromopentyl)-1H-indazole-3-acetamide) is a highly potent, novel synthetic cannabinoid belonging to the indazole-3-acetamide class. Structurally, it is the 5-bromo analog of the widely documented 5F-ADB-INACA, featuring a bromine atom at the terminal position of the pentyl chain, combined with the ultra-effective ADB (1-amino-3,3-dimethyl-2-oxobutyl) head group and the acetamide linker.

In neuropharmacological research, the substitution of terminal alkyl chain hydrogens with halogens is a fundamental variable that dictates CB1/CB2 receptor affinity and metabolic stability. While fluorine (5F-) and chlorine (5Cl-) substitutions have been extensively profiled, the 5-bromo (5BR-) substitution introduces a heavy halogen into the SCRA scaffold. Bromine’s large atomic radius and high lipophilicity drastically alter the molecule’s electronic distribution and steric bulk, making 5BR-ADB-INACA a critical reference standard for mapping the structural-activity relationships (SAR) of heavy-halogenated agonists. Because SCRAs of this potency class pose severe risks of acute toxicity if accidentally exposed, extreme caution and strict in-vitro handling protocols are mandatory. Note: This product is strictly intended for in-vitro research and analytical purposes only.

Key Features and Benefits – Buy 5BR-ADB-INACA Powder

• Heavy-Halogen SAR Mapping: 5BR-ADB-INACA provides researchers with the vital 5-bromo analog required for comparative structural-activity relationship (SAR) studies against 5-fluoro (5F-ADB-INACA) and 5-chloro (5Cl-ADB-INACA) analogs, quantifying how heavy halogen size and lipophilicity dictate CB1/CB2 binding pocket accommodation.
• Indazoleacetamide Core Profiling: Features the acetamide linker (INACA) rather than the carboxamide linker (PINACA), allowing researchers to study the combined steric effects of the methylene spacer and a terminal heavy halogen on receptor efficacy.
• Ultra-High CB1/CB2 Agonist Modeling: As an ADB-core full agonist, it allows the study of maximal receptor activation and subsequent downregulation/internalization at extreme ligand concentrations.
• Forensic Early-Adopter Standard: Essential for forensic and analytical laboratories requiring a pure, verified reference material to proactively calibrate LC/MS and GC/MS instruments, enabling the detection of brominated indazoleacetamides in complex biological matrices.
• Metabolic Profiling: Ideal for analyzing the hepatic breakdown, oxidative debromination, and alkyl chain degradation of heavy-halogenated SCRAs using hepatocyte cultures and liver microsomes.

Product Specifications

• Chemical Name: N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5-bromopentyl)-1H-indazole-3-acetamide
• Common Designation: 5BR-ADB-INACA / 5-Br-ADB-INACA
• CAS Number: Refer to Certificate of Analysis
• Class: Synthetic Cannabinoid / Indazole-3-acetamide / CB1/CB2 Full Agonist / Research Chemical
• Form: Raw Synthetic Powder / Crystalline Solid
• Purity: ≥ 98% (Verified by Independent Third-Party Testing)
• Appearance: White to off-white or pale yellow crystalline powder
• Storage Requirements: Store in a cool, dry, dark environment (ideally -20°C for long-term archival). Keep container tightly sealed under inert gas (Argon/Nitrogen) to prevent degradation.
• Solubility: Soluble in DMSO, ethanol, and organic solvents; practically insoluble in water.

Applications and Usage

5BR-ADB-INACA Powder is exclusively designated for in-vitro (outside a living organism) research and analytical applications. Common laboratory applications include:

• Cannabinoid Receptor Binding Assays: Investigating the compound’s ultra-high affinity and full agonist efficacy at CB1 and CB2 receptors, and contrasting its binding kinetics with 5-fluoro and 5-chloro analogs.
• Heavy-Halogen SAR Studies: Mapping the steric and electronic consequences of the large atomic radius of bromine on the terminal pentyl chain, and determining the limits of the CB1 binding pocket’s accommodation for heavy atoms.
• Metabolic Profiling: Analyzing the hepatic breakdown, debromination, and metabolite identification of 5-bromo substituted cannabinoids using hepatocyte cultures and liver microsomes.
• Forensic and Analytical Calibration: Utilizing 5BR-ADB-INACA as a certified reference material (CRM) for GC/MS, LC/MS, and NMR spectroscopy to validate analytical instruments and identify emerging brominated NPS in biological matrices.

Disclaimer: This product is not for human or veterinary consumption. It must only be handled in controlled laboratory environments by qualified professionals.

Purity and Testing

We guarantee a purity level of ≥ 98% for our 5BR-ADB-INACA Powder. Every batch undergoes rigorous, independent third-party testing to verify chemical identity, absolute purity, and the absence of dangerous residual solvents, heavy metals, or unreacted precursors. Because indazoleacetamides and brominated compounds are prone to degradation, special analytical care is taken to ensure minimal presence of degradation products. Certificates of Analysis (CoA) and Safety Data Sheets (SDS) are provided upon request.

Safety and Handling

WARNING: 5BR-ADB-INACA IS AN ULTRA-POTENT FULL CB1 AGONIST. EXTREME CAUTION IS REQUIRED. ACCIDENTAL EXPOSURE CAN CAUSE SEVERE, LIFE-THREATENING ADVERSE EFFECTS.

• Personal Protective Equipment (PPE): Must wear nitrile gloves, chemical-resistant safety goggles, and a P100 particulate respirator when weighing or transferring the powder.
• Ventilation: Handling must only occur within a certified chemical fume hood to prevent the inhalation of aerosolized particles.
• Accidental Exposure: Avoid direct contact with the bare compound. If skin contact occurs, wash thoroughly with soap and water. Seek medical attention if adverse effects occur. Note: Opioid antagonists like Naloxone are generally ineffective against synthetic cannabinoid toxicity.
• Hygiene: Remove contaminated clothing immediately and wash hands thoroughly after handling, even when PPE is utilized.
• Secure Storage: Keep locked away in a secure, access-controlled laboratory cabinet, out of reach of unauthorized personnel.

Global Shipping and Discreet Delivery

• Global Reach: We ship 5BR-ADB-INACA Powder internationally, in strict compliance with international shipping regulations.
• Discreet Packaging: All orders are dispatched in unmarked, tamper-evident, and odor-proof packaging. The outer packaging does not indicate the nature of the contents.
• Rapid Processing: Orders are processed and shipped within 24 hours of cleared payment. We offer standard and express courier options with full end-to-end tracking.
• Secure Handling: Powders are double-sealed in moisture-barrier bags and placed within sturdy outer containers to prevent damage during transit.

Why Choose Us To Buy 5BR-ADB-INACA Powder?

• Uncompromising Quality: We work directly with top-tier chemical synthesis laboratories and verify every batch in-house and via third-party labs before it reaches you.
• Total Transparency: We provide full analytical data. What is on the label is exactly what is in the bag—no fillers, no impurities, no compromises.
• Expert Customer Support: Our support team understands the nuances of research chemicals and is ready to assist with CoA requests, shipping inquiries, and technical questions.
• Secure Transactions: We utilize SSL encryption and accept secure, discreet payment methods, including major cryptocurrencies (Bitcoin, Monero, Ethereum) and secure bank transfers.

Legal and Safety Compliance

5BR-ADB-INACA Powder is sold strictly as a research chemical and is not approved by the FDA, EMA, or any equivalent regulatory body for human or veterinary use.

It is the sole responsibility of the purchaser to ensure that the acquisition, possession, and use of 5BR-ADB-INACA comply with all local, state, national, and international laws. Warning: 5BR-ADB-INACA is an ultra-potent central nervous system depressant and full CB1 agonist. Ingestion can cause severe, life-threatening psychological and physiological effects, including seizures, coma, and death. It may fall under federal analogue acts or specific synthetic cannabinoid legislation in various jurisdictions (including the USA, UK, and parts of Europe). We do not ship to regions where this compound is explicitly prohibited. By purchasing from us, you affirm that you are a qualified researcher or institutional buyer over the age of 18, and you assume all legal liability for the product upon delivery.

Frequently Asked Questions (FAQ)

Q1: What is 5BR-ADB-INACA?
A: 5BR-ADB-INACA (N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5-bromopentyl)-1H-indazole-3-acetamide) is a novel synthetic cannabinoid from the indazole-3-acetamide class. It features a bromine atom on the terminal pentyl chain and acts as an ultra-potent full agonist at both CB1 and CB2 receptors.

Q2: What makes 5BR-ADB-INACA different from 5F-ADB-INACA?
A: The primary difference is the terminal halogen on the pentyl chain. 5F-ADB-INACA features a fluorine atom (a small, highly electronegative, and stable halogen), while 5BR-ADB-INACA features a bromine atom (a heavy halogen with a large atomic radius and high lipophilicity). This drastic difference in size and polarity alters how the molecule fits into the CB1 binding pocket, making it essential for comparative heavy-halogen SAR research.

Q3: What is the significance of the “INACA” in the name?
A: “INACA” stands for indazole-3-acetamide, meaning there is an extra methylene (CH2) group between the indazole ring and the carbonyl group, compared to the “PINACA” (indazole-3-carboxamide) structure. This alters the spatial orientation of the ADB head group relative to the core, providing a distinct SAR variable for receptor binding studies.

Q4: Can 5BR-ADB-INACA be consumed?
A: Absolutely NOT. 5BR-ADB-INACA is an ultra-potent full agonist at CB1 receptors, far exceeding the potency of natural THC. Ingestion can cause severe, life-threatening psychological and physiological effects, including severe seizures and death, and is strictly prohibited.

Q5: Do you provide a Certificate of Analysis (CoA)?
A: Yes. We provide a comprehensive CoA—including HPLC, GC/MS, and NMR data—for every batch we sell. This guarantees the identity, purity, and mass of the compound.

Q6: Is it legal to buy 5BR-ADB-INACA in my country?
A: Legality varies drastically by country and is subject to change. Because it is a synthetic cannabinoid, it is often controlled under analogue acts or specific NPS bans. We cannot provide legal advice. It is your responsibility to research your local laws regarding this compound before placing an order.

Q7: How should I store 5BR-ADB-INACA for long-term research?
A: For maximum longevity, store 5BR-ADB-INACA in an airtight, amber glass vial under an inert gas (like Argon) in a freezer set to -20°C. Keep away from direct sunlight, heat, and moisture.